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For example, someone with cardiovascular symptoms wouldnt meet the criteria unless they also had gastrointestinal or dermatological symptoms.[ref] One form of MCAS, now called idiopathic anaphylaxis , involves sudden, often random-seeming episodes of throat swelling, itching, wheezing, shortness of breath, stomach pain, nausea, vomiting, diarrhea, and a drop in blood pressure

The joints of people with rheumatoid arthritis contain high levels of mast cells and other immune cells, such as T-cells and B-cells

However, most therapeutic and anti-aging peptides fall between 6 and 25 amino acids