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We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology, a recommended guide for conducting systematic reviews and meta-analyses

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Inflammation and cancer Many cancers arise in areas of chronic inflammation, which plays a major role in tumor invasion, progression, and metastasis, largely through the cytokine-mediated activation of mechanisms involved in tissue repair, cell proliferation and angiogenesis [20, 22, 51,52,53]