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pylori colonizes the gastric mucus layer exclusively and strongly affects the gastric microbial composition, the infection is also associated with distant microbial changes in the small and large intestines (Schulz et al., 2018

5.1.2 Coordination between hepatic detoxification and renal excretion The liver, serving as the central node of the gut-liver-kidney axis, plays a critical role in DKD progression through its metabolic dysfunction

Serum S100B levels and/or the presence of anti-S100B autoantibodies are reliable biomarkers of BBB disruption [48]