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SKU: 13667470184

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Description

Kasckow JW, Lupien SJ, Behan DP, Welge J, Hauger RJ

Transwells were washed with sterile PBS, then used for various analyses

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

Recent mechanistic and epidemiological evidence indicates that conditions such as obesity, type 2 diabetes mellitus, hypertriglyceridemia, coronary heart disease, coronary slow-flow phenomenon, and diabetic peripheral neuropathy share common pathophysiological pathways, most notably insulin resistance, chronic inflammation, lipid metabolism disturbances, and endothelial dysfunction