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2D and Table S1), which may be attributed to rigidification of the GSH surface ligands due to the HIP with DDA

Molecular pathways: reactive oxygen species homeostasis in cancer cells and implications for cancer therapy

L-glutathione is generally considered safe when taken in recommended doses

For instance, in the fibrotic microenvironment where lactate accumulates and is taken up by macrophages and myofibroblasts, p300 has been implicated in promoting lactylation at macrophage-related loci, potentially contributing to the progression of pulmonary fibrosis [81]