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You increase your dose as follows: Week 1 0.6mg as a once-daily injection Week 2 1.2mg as a once-daily injection Week 3 1.8mg as a once-daily injection Week 4 2.4mg as a once-daily injection Week 5 onwards maintenance dose of 3.0mg as a once-daily injection Increasing the dose slowly over time should minimise any unwanted side effects, such as nausea, vomiting and diarrhoea

FIGURE 2 Although various therapeutic approaches including pharmacological and procedural treatments have been considered in melasma management, however, it is a chronic, recurrent, and relapsing skin disorder

That pressure is often what produces symptoms like: shooting leg pain arm numbness burning nerve pain weakness Because of this, treatment approaches often focus on reducing pressure on the disc and nerve