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Dyspepsia, characterized by upper abdominal discomfort, early satiety, or postprandial fullness, may affect a similar proportion of patients and can contribute to reduced caloric intake and weight loss, though it may also impact quality of life if severe or persistent

Zara Cosentino, commenting on the panel's composition, said that while the disclosure of conflicts is a positive transparency measure, it creates a structural problem: "especially when the people who stand to gain from growing access are the ones making the decision." Advisory meetings are subject to federal transparency requirements experts with financial stakes may serve, but relationships must be disclosed and the FDA is expected to explain why the panelist's expertise outweighs the conflict

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Results have even differed widely between similar studies using an identical definition of deficiency, and after stratifying by age [5]