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Some community members are running this sequence deliberately: start with NAD+ precursors (NMN/NR) to raise the baseline pool, then add MOTS-C to put that pool to work, then layer in 5-Amino-1MQ to block the pathway that drains it

Generally, drops of more than 20 mmHg systolic or 10 mmHg diastolic warrant attention, particularly if accompanied by symptoms like dizziness or fatigue