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Concerning pharmacological therapy, medicines used in the treatment of IC are those targeting the diseases confirmed etiology, including mucin substitutes and antihistamines (Amrute and Moldwin, 2007)

Melanotan 2 (MT-2) is a synthetic analog of alpha-MSH that stimulates melanin production with minimal UV exposure

For example, while the S19 vaccine offers temporary protection, it requires frequent boosters and may elicit hypersensitivity

Combined with the RMSD analysis, it can be inferred that after the fluctuation in the first 200 ns, the conformation of CME_b undergoes changes, making it more similar to the characteristics of CME_a.In the CME_c binding mode, the L1 and L4 regions exhibit significant fluctuations during the simulation (Fig