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Long-Term Concerns and the Need for Research While most reported side effects are mild and transient, its important to acknowledge the potential long-term concerns raised in research

Novel formulations and modes of application include extended-release (ER) oral levodopa (IPX203), levodopa powder for inhalation, and levodopa infusion therapies through subcutaneous (foslevodopa/foscarbidopa, ND0612) or intrajejunal pumps (levodopa [entacapone] carbidopa intestinal gel)

Acknowledgements We are grateful for the critical revision of the manuscript by Anamika Dinesh (MD), India

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