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Front Neurosci 12:214

Neutrophil extracellular traps drive intestinal microvascular endothelial ferroptosis by impairing Fundc1-dependent mitophagy

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Consequently, a decrease in CHAC1/BOTCH expression levels, caused by the loss of NRF2, rescues NOTCH1 signaling and restores neuronal stem cell self-renewal (Khacho et al., 2016)