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Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs

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Urine tests , on the other hand, are non-invasive, easier to collect in large quantities, and can sometimes reflect metabolites or breakdown products over a slightly longer period