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In the cumulative toxicity test, the Kunming mice were vein injected with 500 mg kg 1 LAAM GSH-CQDs on days 0, 4, and 7, respectively, and the dose was increased to 1000 mg kg 1 on days 10 and 13 ( n = 3)

The peptide selectively induces p53 nuclear exclusion and apoptosis in hydrogen peroxide-induced senescent Leydig cells in vitro, confirming direct cellular targeting

TNF-, which is secreted by microglia stimulated by amyloid-1-42, induced an increase in MHCI expressed by hCMEC/D3 and facilitated T-cell transmigration (Yang et al., 2013)

You can react more easily to topical products that were previously fine and have a response to environmental triggers [like heat and cold], says Robyn Gmyrek, M.D., board-certified dermatologist at UnionDerm in New York City