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Despite the widely promulgated risks associated with cigarette smoking in CD, more incisive data are required to further elucidate the actual relationship between smoking and disease pathways, while accounting for the several negative cofactors prevalent in smokers which cast uncertainty on the magnitude of the direct effect of smoking on disease pathophysiology and the efficacy of therapy

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While implementing policies fully compliant with MPOWER could further reduce smoking prevalence, the predicted prevalence in 2025 would still be above the Tobacco Free Ireland target of 5%

LC-MS/MS was carried out at the University of Toledo Shimadzu Laboratory for Pharmaceutical Research Excellence