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Intranasal administration delivers Semax and Selank directly to the central nervous system via olfactory nerve pathways, bypassing first-pass hepatic metabolism and achieving rapid onset (2030 minutes for Semax, 4560 minutes for Selank)

Disinfect rubber stoppers on both the BPC-157 and bacteriostatic water vials before each access

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As pointed out [60], it has to be the counteraction of the reduced capillary perfusion pressure, increased cerebral blood volume, venous flow obstruction, increased intracranial pressure and blood-brain barrier disruption, resulting in a decreased cerebral blood flow [60]