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The FDA black box warning on antidepressant suicide risk in young adults: more harm than benefits

For example, thioredoxins are a family of redox active proteins of approximately 12 kDa responsible for mediating numerous cytoplasmic functions influenced by available cysteine residues in the monomeric protein

in contrast, GSS knockout depletes GSH but still permits glutamate consumption for -glutamyl-peptide synthesis, and does not alter ferroptosis sensitivity under cystine starvation