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Complete bed rest isnt necessary, but avoid: Running or jogging Climbing multiple flights of stairs repeatedly Heavy lifting or squatting High-impact sports Elevation: Keep your leg elevated when sitting or lying down to reduce swelling

Hence, pharmaceuticals that target the NRF2 pathway can influence multiple pathways involved in the neurodegenerative process, and therefore hold potential to become therapies that can significantly modify the course of neurodegenerative diseases

This makes it a potential therapeutic option for individuals with growth hormone deficiencies

Supplementary material The Supplementary Material for this article can be found online at: References 1 AdoR.GuzikT