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BBB leakage and memory loss are linked to the decrease in tight junctions in brain endothelium and pericyte coverage, and inflammation in brain tissue in both type 1 diabetes mellitus and type 2 diabetes mellitus mice [78]

Several studies have shown that cancers with a strong association with bilirubin include liver, lung, and digestive tract cancers such as gastric ( rs887829 and rs4149056 genes (genes that cause elevated levels of bilirubin) had a 17% reduced risk of suffering from lung cancer, a percentage that had an even larger value in the smoker population

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