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The FDAs MRTP authorization of VLN ushered in a new reality a combustible cigarette carrying an authorized harm reduction claim supported by extensive scientific and clinical studies, most of which were funded by federal health agencies, said James A

Epithelial barrier integrity is also adversely affected following exposure to a diverse range of inhaled substances including diesel exhaust particulates, ambient particulate matter, acrolein, asbestos, ozone, wood smoke particulates, and e-cigarette flavorings (Peterson et al., 1993