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NG239 Evidence review D: tests for identifying cause of vitamin B12 deficiency

The ratio of postsynaptic mRFP- -actin labeled spines juxtaposed to Synapsin or VGLUTl spines was not different from control treated neurons suggesting treatment-induced spines are forming functional synapses (Figure 9A-D)

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That is especially important when the final conjugate must function as a metabolite standard, a mechanistic tool for covalent drug studies, a transporter or mercapturate-pathway probe, or a tagged glutathione derivative for assay development