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According to Heal et al., titled Interactions Between Prescription Stimulants and Other Substances, published in Neuropharmacology (2018) , mixing Adderall with other stimulants amplifies dopamine release, significantly increasing the likelihood of cardiovascular strain and overdose

A smoking article according to any one of claims 1 to 4, wherein the filter is joined to the rod of smokeable material via an annular extension to the filter

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"The term 'new' referred to 'newly misused' as in almost all cases the substances had been first synthesised many years ago, often as potential therapeutic agents," said King