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He also said the FDA is building efficiencies into the regulatory process that will make it less costly for companies to apply over time

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15 , 16 (See also Chapter 10.) Throughout the 2010s, further declines in smoking prevalence occurred in the wake of large tobacco excise increases, plain packaging, and increasingly comprehensive smoking bans (see Figure A1.6 and Section 15.7)

However, the very same burning process that releases the tobacco flavors and nicotine also produces over 6,000 chemicals, of which about 100 have been identified as causes or potential causes of smoking-related diseases, such as lung cancer, cardiovascular disease, and emphysema