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2017 Cell study used 5 mg/kg intraperitoneal injection three times per week in aged mice, with treatment periods of several weeks the three-times-weekly dosing suggests the peptide maintains sufficient functional concentrations for at least 48-72 hours per dose (PMID: 28340339)

Individuals with Allergies to Ingredients: Sensitivity to any component in the injection could result in allergic reactions

The same research group also published a study in older adults with HIV showing similar benefits, including reduced oxidative stress and improved mitochondrial fatty acid oxidation (Kumar et al., Antioxidants, 2020) [30]