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Additionally, AESN has been reported to activate INS-1 cells under high-glucose conditions (117), with the underlying mechanisms illustrated in Figure 2

Glutathione production depends on nutrients that provide key amino acids, such as cysteine

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BRET measurements were carried out in HEK293T cells co-expressing Nluc-fused mas-GsBP1, mas-GsBP2, mas-KB1753 (in D, E and F), mas-GRK RH (in G), or mas-PRG RH (in H), with either wild-type (WT) or constitutively active (QL) mutants of Gi3 (in D), Go (in E), Gz (in F), Gq (in G), or G13 (in H) fused to a YFP, as indicated