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Since acute exposure to non-flavored electronic cigarette aerosol was also shown to activate TRPA1 receptors in endothelial cells, this suggests that combined effects of propylene glycol and vanilla chemical flavorant may potentiate the adverse effect of each other or may exert greater side effects in vivo (105)

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But research published in the Journal of the American Dental Association (JADA) shows that hookah smoking is linked with gum disease, dry socket, cancers of the head, neck and mouth and other serious conditions

There has been little change in the prevalence of smoking since the previous year (32% were current smokers in 2001 and 35% in 2000)