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Efficacy-wise, AOD-9604 produces modest results (2-3 kg over 12 weeks in trials) compared to GLP-1 agonists dramatic weight loss

PMID: 219 WangRLiBHuangBLiYLiuQLyuZet al

However, given the slow-healing nature of disc tissue, preclinical studies and anecdotal reports suggest research cycles often last for several weeks to months to observe meaningful changes

In analyzing pain scores, an interesting correlation reached statistical significance: patients with a higher BMI reported higher postoperative pain levels compared with others, even though they still experienced an overall improvement in pain after the laser procedure