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En situaciones de elevada liplisis, como el pico de lactacin y en estados cetnicos, la funcin metablica de la l-carnitina juega un papel fundamental, actuando como buffer de los grupos acetil, dando lugar a la formacin de acetil-carnitina en el hgado

Additionally, none of these models recapitulates the three-dimensional (3D) bile canaliculus structures (thin and elongated lumina) observed in tissue 16 , making it difficult to model complex disease states or recapitulate patient-specific traits, both of which are essential for precision medicine and early diagnosis

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