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3.1.4 Chronic Granulomatous Disease CGD is a primary immunodeficiency syndrome that is characterized by defects in respiratory burst of phagocytes, leading to serious and life-threatening infections (Squire et al., 2020)

The mechanism formally parallels the -elimination reaction catalyzed by PLP-dependant enzymes which accept cysteine thioethers as substrates and likely play a role in the renal toxicity and carcinogenicity of halogen-alkenes through their urinary metabolites [125]

Cholesterol and matrisome pathways dysregulated in astrocytes and microglia

The only amino acid in this series that led to measurable ROS production was cysteine (Fig