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Epidemiology, pathophysiology, diagnosis, and management of cerebral toxoplasmosis

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However, it is important to note that erythrocytes generate ROS primarily as a result of (i) hemoglobin oxidation, which can be considered as an iron-mediated Fenton reaction, (ii) the activity of NAPDH oxidase and (iii) xanthine oxidoreductase, while in nucleated cells ROS are mainly generated in the mitochondrial electron transport chain

10.4049/jimmunol.168.11.5811 94 VidalC.Gmez-HernndezA.Snchez-GalnE.GonzalezA.OrtegaL.Gmez-GeriqueJ