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Store the vial in a cool, dry place between 2-8 C, protected from light, and use reconstituted solution promptly

Ascorbic acid is notorious for breaking down when exposed to sunlight and oxygen whereas SAP has been shown to be more stable

Pyruvate kinase (PK) catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to ADP with the consequent formation of pyruvate and ATP

In the chronic kidney disease (CKD) state, declining renal function leads to substantial urea excretion into the intestinal tract, where it is hydrolyzed by microbial urease to ammonia, converting to ammonium hydroxide and elevating luminal pH (100)