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Other copper-peptide complexes exist in research literature, but GHK-Cu is the one most closely associated with the term because it was the first to be isolated and remains the most widely referenced in copper-peptide research

Additionally, GHK-Cu modulates the activity of matrix metalloproteinase-13 (MMP-13), an enzyme that is overactive in degenerative joint diseases and contributes to cartilage degradation

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