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This ratio is the primary determinant of the cellular redox state
Targeting mitochondrial ROS-mediated ferroptosis by quercetin alleviates high-fat diet-induced hepatic lipotoxicity
HEK-293T cells were grown in high glucose (4.5 g/L glucose) Dulbecco's modified Eagle's medium (DMEM, Thermo Fisher Scientific) supplemented with 10% fetal bovine serum (FBS, Natocor), penicillin/streptomycin (100 units/mL and 100 g/mL, respectively, Thermo Fisher Scientific) and 110 mg/L of sodium pyruvate (Thermo Fisher Scientific) in a 37 C humidified incubator containing 5% CO 2
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