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If left untreated, BPH can lead to permanent bladder damage (decompensation) where the bladder can no longer squeeze, recurrent bloody urine, severe infections, and irreversible kidney failure due to hydronephrosis

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Moreover, S100A8/S100A9 complex binds to endothelial cells via the S100A9 subunit interacting chiefly with heparin and heparan sulfate proteoglycans (125), contributing to the immobilization of the myeloid cell-derived S100A8/S100A9 complex on endothelium in human inflammatory diseases

Once your liver stores were fully replenished, your schedule was reduced to a maintenance pace designed simply to top off your levels and keep them stable for life