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Reference: AIC50 Aicar 50mg AICAR is an analog of adenosine monophosphate (AMP), a nucleotide that is considered to play an important role in cellular energy metabolism

For some people, the answers may lie in the tiny powerhouse of the cell: the mitochondria

Research published eLife (PMID: 36345724) sought to answer the questions Do differences in metabolites in the brain affect our capacity for motivation?, If that is the case, could nutritional interventions that affect metabolite levels be an effective vehicle to improve motivated performance? The researchers measured levels of the antioxidant glutathione in the nucleus accumbens of humans and rats and compared these levels to performance in effort-related tasks that assessed motivation

Maha, A