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This stability is considered a direct consequence of its gastric origin: a peptide evolved to remain functional in the highly acidic, protease-rich environment of the stomach

4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas

(October 2024)

But all the tools introduced to tackle with uncertainty have sides of subjective and normative characteristics and use of power in themselves that sometimes the sole reason of facing uncertainty is not enough to justify them and they seem to be insufficient in a way that they produce even more uncertainty