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It promotes the formation of new blood vessels at injury sites, modulates nitric oxide production, and upregulates growth-hormone receptors on tendon and ligament fibroblasts

Its additional immune-modulating properties, through the induction of interleukin-6 (IL-6), add another layer to its homeostatic and neuroprotective profile

Additionally, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3), BNIP3-like protein (BNIP3L or NIX), and FUN14 domain-containing protein 1 (FUNDC1), which also contain LIR motifs, promote the formation of autophagosomes (Wang S

The potential of CRISPR/Cas9 gene editing as a treatment strategy for inherited diseases