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Rarely, ingestion of large quantities of ascorbic acid have been associated with fatal cardiac arrhythmias in patients with iron overload

J Cell Biol 146:10331044 Ezratty EJ, Partridge MA, Gundersen GG (2005) Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase

However, another cyclic peptide inhibitor for CXCR4, LY2510924, did not improve the efficacy of sunitinib in patients with RCC [391], and was ineffective in SCLC patients [392]

This term refers to the proportion of a substance that enters the circulation when introduced into the body and is so able to have an active effect