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Besides being involved in the pathophysiology of several types of malignant neoplasms, not only in the lungs, smoking represents the first cause of chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD) [5, 6], as well as a major determinant of cardiovascular (CV) diseases, such as myocardial infarction, stroke and peripheral arterial diseases

Harm reduction is practised to minimise risk in other ways, e.g.: Helmet use for bicycles and motorcycles Vaccines to minimise the effect of Covid infections Using contraception for safe(er) sex Clean needles and syringes for drug users in supervised conditions Understanding The Risk Continuum In THR, the Royal College of Physicians (RCP) states that the hazard to health, arising from long-term vapour inhalation from e-cigarettes, is unlikely to exceed 5% of the harm from smoking tobacco

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