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Statements Data availability statement The datasets presented in this study can be found in the Genome Sequence Archive (24), China National Center for Bioinformation/Beijing Institute of Genomics, Chinese Academy of Sciences (GSA-Human: HRA004967) that are publicly accessible at Ethics statement The studies involving human participants were reviewed and approved by Ethics Committee of Institute of Pediatric Research, Children's Hospital of Hebei Province

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74 The physiological significance of this pressure natriuresis is uncertain, although it is probably involved in certain pathological conditions such as malignant hypertension