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Other plant-derived compounds, such as citronellal and perillaldehyde, induce ROS overproduction, resulting in mitochondrial and DNA damage (Tian et al., 2016

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In anti PD-1 resistant T cell rejection models, the application of type I PRMT inhibitors PT1001B or GSK3368715 can increase the number of tumor-infiltrating T cells and increase the efficacy of anti-PD-1 therapy