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Osteoclastogenesis is upregulated due to increased expression of receptor activator of nuclear factor kappa-B ligand (RANKL) and cathepsin K, resulting in enhanced bone resorption (Table 1) (Maruotti et al., 2017)

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Figure 3 5 The management of siLNs: superselective dissection and active surveillance In general, lateral cervical metastasis most commonly occurs in compartments II-IV, as do siLNs (97)

Research Insight: A systematic review in The Journal of Orthopaedic & Sports Physical Therapy (2012) found that combining hands-on therapy with corrective exercises is more effective in managing plantar fasciitis than using either approach alone