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These findings suggest that the microbiome may contribute to the pathogenesis of depression through complex interactions involving microbial metabolites, neurotransmitter regulation, and immune system modulation

Important to note, both PLP and 5-methyltetrahydrofolate require riboflavin in their biosynthesis using the active forms of riboflavin, FMN, and FAD, respectively (89) (Figure 4)

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After reaching the gut, the liposomal glutathione sticks to the lining of the intestine, so more of the glutathione antioxidant passes into the bloodstream