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We induced myocardial isoprenaline lesions (as described [24] with one or two applications of isoprenaline (75 mg/kg or 150 mg/kg s.c.))

However, the effectiveness of B12 injections may vary from person to person

Route Subcutaneous injection (abdomen, thighs, or upper arms) Schedule Once daily, 5 days per week with gradual titration Injection Sites Rotate injection sites to prevent tissue irritation Dosing Consistent 2.0 mg per injection for simplified scheduling Use sterile technique when handling and administering Cycle Length: 812 weeks typical

SURF1 deficiency: expanding on disease phenotype and assessing disease burden by describing clinical and biochemical phenotype