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Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent

This progression is fueled by the seemingly uncapped potential of the obesity drug market, which is expected to grow by as much as $100 billion by 2030 (1)

The supervised approach is what lets you get the upside while someone qualified is watching for anything that doesn't fit

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