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As expected, the induction of primitive streak and intermediate mesoderm was initiated by treatment with CHIR99021 (a Wnt agonist) and Noggin (a BMP inhibitor), the former essential for mesoderm lineage specification and the latter represses lateral plate mesoderm differentiation [11]

& Baumgartner, M., 1998

De Luna N, Turon-Sans J, Cortes-Vicente E, Carrasco-Rozas A, Illn-Gala I, Dols-Icardo O, et al

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