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M7824 (MSB0011359C), a bifunctional fusion protein targeting PD-L1 and TGF-, in patients with heavily pretreated CRC: Preliminary results from a phase I trial

For patients at our Doral clinic who present with injuries across more than one joint or muscle group, this systemic reach is a key reason TB-500 is selected over a localized peptide alone

PMID: 41455083

In monotherapy, the most promising results were observed with the administration of 40 M fisetin, leading to a reduction in the viability of cancer cells to approximately 50% compared to the control group and the induction of apoptosis in about 20% of the cells [139]