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A perfectly smokable and delicious cigar can be rolled from well-aged, whole leaf tobacco of just about any variety

3 Compared to mainstream smoke, sidestream smoke contains higher levels of polycyclic aromatic hydrocarbons (PAHs), N -nitrosamines, aromatic amines, carbon monoxide, nicotine, ammonia, pyridine and the gases 1,3-butadiene, acrolein, isoprene, benzene, and toluene

To do so, the research team first took mice with the CHRNA5 gene variant and used state-of-the-art brain imaging technologies to see if they had hypofrontality