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In the end, this can hold a general counteracting potential and contributing innate neurotransmitter potential, matching with the original cytoprotection concept perception holding equal cell protection (necrosis prevention) against a variety of different agents, thus, a pleiotropic beneficial effects that should be obtained with cytoprotective agents application that could also have neurotransmitter background as well

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The glutamate residues are added by an amide linkage to the -carboxylate group of the folate derivative