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Cross-sectional studies showed that Agathobacter and Prevotella_9 abundance correlated positively with eGFR and negatively with microalbuminuria( 3.1.4.2 Translational difficulties between animal models and human studies Approximately 65% of studies cited in this review are based on animal models (primarily db/db mice and STZ-induced diabetic rats), 25% are human cross-sectional studies, and only 10% are human prospective cohort studies

Defects in the IL-17 pathway are an important cause of early-onset CMC

DAT belongs to the SLC6 family of Na + /Cl dependent transporters, and is composed of 12 transmembrane domains and intracellular N- and C-termini