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The pivotal NEJM trial reported that the percentage of patients experiencing symptoms of growth hormone excess including joint pain, peripheral edema, and muscle aches was lower than seen in earlier large trials of growth hormone itself in HIV-infected patients

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Lipogenesis Inhibition In adipocyte models, 5-Amino-1MQ suppresses lipogenesis (EC50 = 30 M in 3T3-L1 adipocytes) while increasing intracellular NAD+ concentrations